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Pritchard, Jonathan
One or more keywords matched the following items that are connected to Pritchard, Jonathan
Item TypeName
Concept Gene Expression Regulation
Concept Gene Expression Regulation, Developmental
Concept Down-Regulation
Concept Gene Expression Regulation, Neoplastic
Academic Article Understanding mechanisms underlying human gene expression variation with RNA sequencing.
Academic Article Gene expression levels are a target of recent natural selection in the human genome.
Academic Article Exon-specific QTLs skew the inferred distribution of expression QTLs detected using gene expression array data.
Academic Article Genomics: ENCODE explained.
Academic Article The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels.
Academic Article Revealing the architecture of gene regulation: the promise of eQTL studies.
Academic Article DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines.
Academic Article Clonal origin and evolution of a transmissible cancer.
Academic Article DNase?I sensitivity QTLs are a major determinant of human expression variation.
Academic Article High-resolution mapping of expression-QTLs yields insight into human gene regulation.
Academic Article Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels.
Academic Article Epigenetic modifications are associated with inter-species gene expression variation in primates.
Academic Article Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature.
Academic Article The genetic and mechanistic basis for variation in gene regulation.
Academic Article Genomic variation. Impact of regulatory variation from RNA to protein.
Academic Article Identification of genetic variants that affect histone modifications in human cells.
Academic Article Primate transcript and protein expression levels evolve under compensatory selection pressures.
Academic Article The chromatin architectural proteins HMGD1 and H1 bind reciprocally and have opposite effects on chromatin structure and gene regulation.
Academic Article The functional consequences of variation in transcription factor binding.
Academic Article msCentipede: Modeling Heterogeneity across Genomic Sites and Replicates Improves Accuracy in the Inference of Transcription Factor Binding.
Academic Article Genetic Variation, Not Cell Type of Origin, Underlies the Majority of Identifiable Regulatory Differences in iPSCs.
Academic Article RNA splicing is a primary link between genetic variation and disease.
Academic Article Coregulation of tandem duplicate genes slows evolution of subfunctionalization in mammals.
Academic Article Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice.
Academic Article Whole Genome Sequencing Identifies a Novel Factor Required for Secretory Granule Maturation in Tetrahymena thermophila.
Academic Article Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution.
Academic Article Post-translational buffering leads to convergent protein expression levels between primates.
Academic Article Trans Effects on Gene Expression Can Drive Omnigenic Inheritance.
Academic Article Landscape of stimulation-responsive chromatin across diverse human immune cells.
Academic Article Chromatin accessibility dynamics in a model of human forebrain development.
Academic Article Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression.
Grant Computational methods for modeling lineage-specific gene regulation
Grant Analysis and interpretation of noncoding regulatory variation
Grant Genetic and epigenetic controls of gene regulation
Grant Integration of functional data and GWAS to elucidate genetic basis of diseases
Academic Article Precise modulation of transcription factor levels identifies features underlying dosage sensitivity.
Academic Article Systematic differences in discovery of genetic effects on gene expression and complex traits.
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